Song Li

Department Bioengineering
University of California, Berkeley


Stem cells play important roles in tissue remodeling, regeneration and disease development. The research in our cell and tissue engineering laboratory is focused on: (1) the role of stem cells and the underlying mechanisms in tissue regeneration and vascular disease development, (2) how biophysical factors such as surface micro/nano topography, matrix mechanical properties and hemodynamic forces regulate stem cell functions and cell reprogramming, and (3) how the micro/nano structure and the chemistry of biomaterials can be engineered to recruit stem cells and promote tissue regeneration. We take a multidisciplinary approach to combine the principles and technologies in engineering, biology and medicine to address these issues at the interfaces of stem cell engineering, tiissue engineering, biomaterials and mechanobiology.